Reply to "Unrealistic nonphysiological amounts of reagents and a disregard for published literature"

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Posttranslational modifications of proteins in the pathobiology of medically relevant fungi

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Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans

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Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

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Conflicting interests in the pathogen-host tug of war : fungal micronutrient scavenging versus mammalian nutritional immunity

Funding: The authors are supported by the European Research Council (STRIFE project funded on grant number ERC-2009-AdG-249793, http://erc.europa.eu). AJPB is also supported by the Wellcome Trust (grant numbers 080088, 097377, www.wellcome.ac.uk) and the UK Biotechnology and Biological Sciences Research Council (grant number BB/F00513X/1, www.bbsrc.ac.uk). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals

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Candida auris undergoes adhesin-dependent and -independent cellular aggregation

Acknowledgments We are grateful to Rhys Farrer (MRC CMM, University of Exeter) and Sophie Shaw (CGEBM, University of Aberdeen) for guidance on bioinformatic analysis, to Louise Walker (University of Aberdeen) for advice on macrophage work, and to Neil A. R. Gow (MRC CMM, University of Exeter) and Dhara Malavia (MRC CMM, University of Exeter) for discussing their unpublished results. We thank Gillian Milne (Microscopy & Histology Facility, University of Aberdeen) for technical assistance with electron microscopy. Candida auris strains were kindly provided by Anuradha Chowdhary (Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India), Public Health England (PHE) (Bristol, UK), and the Mycotic Diseases Branch of the Centers for Disease Control and Prevention (CDC) (Atlanta, GA, USA). Funding This work was supported by a PhD studentship (MR/P501955/1) from the Medical Research Council (MRC) Centre for Medical Mycology at the University of Exeter, UK 694 (MR/N006364/2). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Preprin

Early-expressed chemokines predict kidney immunopathology in experimental disseminated Candida albicans infections

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Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen

The authors thank E. Veal for intellectual input. This work was funded by the UK Biotechnology and Biological Research Council [J.Q. BB/K016393/1; A.J.P.B. BB/K017365/1], the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) [D.M.M. NC/N002482/1] and the Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology [097377]). D.M.M. and A.J.P.B. are also supported by the MRC Centre for Medical Mycology at the University of Aberdeen (MR/N006364/1).Peer reviewedPublisher PD